Culture is the most important intangible aspect of an organization that ensures its success. The important values relevant to the organizations are openness, confrontation, trust, authenticity, proactivity, autonomy, collaboration and experimentation. The study is an attempt to explore the dynamics of organizational culture in Indian organizations and Middle East organizations using OCTAPACE framework. The study aims to study the differences of various cultures of organizations in India and Middle East and highlight the factors behind it. In the current study, 140 responses were obtained on OCTAPACE profile questionnaire developed by T.V. Rao (1999). The study found the significant differences on various dimensions of OCTAPACE culture, organizational ethos and values which are linked to each other. The study addresses the meek aspects of culture in terms of beliefs and values that exist in the organization. It further helps in building a sustained competitive advantage and generating the desired organizational performance. The outcomes of the study can be helpful in right selection of personnel when hiring for different demographics. The study will not only add value to the core operative functions of HR, but enable best fit.