In the contemporary epoch, the demands for hospitality and tourism services are swiftly increasing. Consequently, hotel employees are facing tremendous job pressure at the workplace. Such job pressure leads to job stress among them. However, this study aims to identify the effect of job stress on job satisfaction in hospitality and tourism employees in West Bengal, India. For the purpose of the study, feedback from 353 hotel employees has been considered. Factor analysis and multiple regression analysis have been performed using SPSS. Multiple regression analysis has been carried out to verify the associations between job stresses on job satisfaction. The study has identified five different factors of stress which are ‘Working Hours’, ‘Expectations from Management’, ‘Social Role of Work’, ‘Leave and Work Load’, ‘Over Expectations of Management’. The study concludes with the findings that Working Hours, Over Expectations of Management, and Social Roles of Work are the “Eustress” factors for the hotel employees. On the other hand, Leave and Work Load and Expectations from Management are the “Distress” factors for the hotel employees. However, stress-free employees can perform better and if the employees feel satisfied, the ultimately organizational goals could be achieved smoothly. An organization should establish strong policies to guide employees towards a clear direction and organize frequent training programs for employees as a moderating stress treatment.