This research paper examines the interpersonal relationship between gender, self-efficacy, and entrepreneurial career choice. The present study has been conducted in Uttarakhand, a province of India. An item pool was developed on the basis of focus group interviews and literature survey. A scale was developed on the basis of item pool after an item analysis for checking its consistency and reliability and was included in the questionnaire. The questionnaire was administered on 880 graduation final year students studying in different colleges. An interpersonal relationship between gender, self-efficacy, and entrepreneurial career choice was examined using Pearsons chi-square test and Students t-test. Results show significant relationship between gender and self-efficacy, self-efficacy and entrepreneurial career choice, and gender and entrepreneurial career choice. Male respondents were found to have higher level of self-efficacy than female respondents. This paper also explores that male respondents are more likely to opt for an entrepreneurial career than females.