The Micro, Small and Medium Enterprises (MSMES) have always been considered as growth engine of the Indian economy. MSMES are well known for its lower investment and technology requirement. After agriculture, this sector holds second position in generating employment opportunities in Indian economy. MSMES also enhance industrialization in rural and backward area thereby reduce regional imbalances and assure equitable distribution of national income and wealth. Despite its contribution and significance in the Indian Economy, the MSME sector has been facing various hurdles since long. After the liberalization and globalization in India since 1991, this sector is facing keen competition from domestic organizations as well as from the MNCS because of the improved technology in the market. This present paper deals with growth and development of MSMES in India and also highlight the problem and prospects of MSMES in India.