Instructor?s decision to choose a suitable instruction methodology depends upon the maturity level of learners. Literature reveals the use of andragogy or pedagogy as instruction methodology. Self-concept of learner, experience, learning motivation, orientation to learning and domain of instruction are identified as the factors of learner?s maturity level. The current study focused on examining the relative effectiveness of andragogy and pedagogy in teaching higher level informative course to postgraduate management learners of an autonomous business school in Rajasthan. Effectiveness of learning is examined through measuring learning output. Analysis of results reveals relatively high maturity level of learners and therefore the preferred methodology of instruction shall be andragogy only. Instructors are suggested to use practical application through use of videos, experiential exercises, and group activities in which learners can share their experiences.