This research finds the relationship of career development, psychological empowerment, and innovative output in the STEM fields for women employees. Data was collected from 401 women employees in select cities through an experimental survey. SPSS and SEM Amos were used to analyze the data. Descriptive statistics was found for the data before regression. The findings indicate that the relationship between psychological empowerment and innovative output is mediated by career development. Workplace can continue to provide psychological empowerment programs for female employees to promote the participation of more women in STEM careers. This paper used the Value Percept Theory and Social Exchange Theory to explain psychological empowerment in STEM sector in India. And both of these are a novelty of this paper.