In terms of environmental and socioeconomic problems, the COVID-19 pandemic has resulted in a global crisis. It has changed the generation of waste and its disposal in both quantity and quality, posing fundamental challenges to policymakers in making decisions that will ensure long-term environmental management. The current study has reflected the existing difficulties of the waste management system in combating increased waste generation along with disposable PPE (Personal Protective Equipment). The risk of COVID-19 infection from contaminated waste is high, particularly in developing countries where waste management measures are sadly inadequate. As a result, the importance of developing waste management strategies would help address the environmental, social, and economic difficulties in the face of the global financial crisis through analysis of various case studies across countries. It would help to incorporate the proposed strategies across municipal bodies in developing countries to achieve sustainability and introduction of new policy frameworks in order to manage waste effectively across municipalities.